Methadone-Mediated Autonomic Functioning of Male Patients with Heroin Dependence: The Influence of Borderline Personality Pattern
Open Access Peer-reviewed Research Article Wei-Lieh Huang, Yu-Hsuan Lin, Terry B. J. Kuo, Li-Ren Chang, Ying-Zai Chen, Cheryl C. H. Yang Published: May 22, 2012 https://doi.org/10.1371/journal.pone.0037464 Abstract Background We hypothesize that the population with borderline personality shows different autonomic response to methadone compared to individuals with other personalities. This study applies heart rate variability (HRV) measurements and the Tridimensional Personality Questionnaire (TPQ) to examine this hypothesis. Methodology/Principal Findings Forty-four male patients with heroin dependence were recruited from a methadone…