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Trustworthiness appraisal deficits in borderline personality disorder are associated with prefrontal cortex, not amygdala, impairment

Trustworthiness appraisal deficits in borderline personality disorder are associated with prefrontal cortex, not amygdala, impairment

Eric A.Fertuckabc JackGrinbandbcd J. JohnMannbc JoyHirschde KevinOchsnerf PaulPilkonisg JeffErbeac BarbaraStanleybc https://doi.org/10.1016/j.nicl.2018.101616Get rights and content Under a Creative Commons license open access Highlights •BPD is associated with sensitivity to signals of interpersonal betrayal and misplaced trust in others. •BPD subjects judged faces to be less trustworthy than controls. •Amygdala activity did not correlate with trustworthiness, but was modulated robustly by fearfulness of the stimulus. •Prefrontal cortex, not amygdala, was modulated by trustworthiness. •BPD was associated with reduced prefrontal activity, and the…

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The relationship between childhood traumas, dissociation, and impulsivity in patients with borderline personality disorder comorbid with ADHD

The relationship between childhood traumas, dissociation, and impulsivity in patients with borderline personality disorder comorbid with ADHD

Original Articles Filiz Kulacaoglu, Mustafa Solmaz, Ferhat Can Ardic, Ercan Akin & Samet Kose https://doi.org/10.1080/24750573.2017.1380347 Objective: Previous studies reported that there were significant associations between Attention-deficit/hyperactivity disorder (ADHD) and borderline personality disorder (BPD). In this study, we aimed to examine complex relationship between childhood trauma, impulsivity, dissociative symptoms, and the impact of ADHD on this relationship in a sample of patients with BPD. Methods: Our samples consisted of 165 BPD patients (128 female, 37 male) and 165 healthy subjects (128…

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Borderline personality disorder and childhood trauma: exploring the affected biological systems and mechanisms

Borderline personality disorder and childhood trauma: exploring the affected biological systems and mechanisms

Published: 15 June 2017 Nadia Cattane, Roberta Rossi, Mariangela Lanfredi & Annamaria Cattaneo Abstract Background According to several studies, the onset of the Borderline Personality Disorder (BPD) depends on the combination between genetic and environmental factors (GxE), in particular between biological vulnerabilities and the exposure to traumatic experiences during childhood. We have searched for studies reporting possible alterations in several biological processes and brain morphological features in relation to childhood trauma experiences and to BPD. We have also looked for…

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The relationship between non-suicidal self-injury and borderline personality disorder symptoms in a college sample

The relationship between non-suicidal self-injury and borderline personality disorder symptoms in a college sample

Borderline Personal Disord Emot Dysregul. 2014; 1: 14. Published online 2014 Sep 25. doi: 10.1186/2051-6673-1-14 PMCID: PMC4579519 PMID: 26401298 Lauren J Brickman, Brooke A Ammerman, Amy E Look, Mitchell E Berman, and Michael S McCloskey Author information Article notes Copyright and License information Disclaimer This article has been cited by other articles in PMC. Abstract Background Non-suicidal self-injury (NSSI) is a major concern in both clinical and non-clinical populations. It has been approximated that 65-80% of individuals with borderline personality disorder…

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Fostering Self-Compassion and Loving-Kindness in Patients With Borderline Personality Disorder: A Randomized Pilot Study

Fostering Self-Compassion and Loving-Kindness in Patients With Borderline Personality Disorder: A Randomized Pilot Study

Clinical Psychology and Psychotherapy Clin. Psychol. Psychother. (2016) Practitioner Report   Albert Feliu-Soler,1,2,3 Juan Carlos Pascual,1,2,3 Matilde Elices,1,2,3,4 Ana Martín-Blanco,1,2,3 Cristina Carmona,1,2,3 Ausiàs Cebolla,5,6 Vicente Simón7 and Joaquim Soler1,2,3* 1 Servei de Psiquiatria, Hospital de la Santa Creu i SantPau, Barcelona, Spain 2 Institut d’Investigació Biomèdica SantPau—IIB SantPau, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Spain 3 Universitat Autònoma de Barcelona, Barcelona, Spain 4 Programa de Cognición. Instituto de Fundamentos y Métodos en Psicología, Facultad de Psicología,…

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Dialectical behavior therapy alters emotion regulation and amygdala activity in patients with borderline personality disorder

Dialectical behavior therapy alters emotion regulation and amygdala activity in patients with borderline personality disorder

J Psychiatr Res. Author manuscript; available in PMC 2014 Dec 11. Published in final edited form as: J Psychiatr Res. 2014 Oct; 57: 108–116. Published online 2014 Jul 2. doi: 10.1016/j.jpsychires.2014.06.020 PMCID: PMC4263347 NIHMSID: NIHMS646634 PMID: 25038629 Marianne Goodman,a,b,d,* David Carpenter,c Cheuk Y. Tang,c Kim E. Goldstein,a Jennifer Avedon,b Nicolas Fernandez,b Kathryn A. Mascitelli,b Nicholas J. Blair,b Antonia S. New,a,b Joseph Triebwasser,a,d Larry J. Siever,a,b,d and Erin A. Hazletta,b Author information Copyright and License information Disclaimer The publisher’s final edited version…

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Borderline Personality Disorder in Transition Age Youth with Bipolar Disorder

Borderline Personality Disorder in Transition Age Youth with Bipolar Disorder

Acta Psychiatr Scand. Author manuscript; available in PMC 2016 Oct 1. Published in final edited form as: Acta Psychiatr Scand. 2015 Oct; 132(4): 270–280. Published online 2015 Apr 11. doi: 10.1111/acps.12415 PMCID: PMC4573347 NIHMSID: NIHMS670411 PMID: 25865120 Shirley Yen, Ph.D.,1,2 Elisabeth Frazier, Ph.D.,1,4 Heather Hower, M.S.W.,1 Lauren M. Weinstock, Ph.D.,1,2 David R. Topor, Ph.D.,3 Jeffrey Hunt, M.D.,1,4 Tina R. Goldstein, Ph.D.,5 Benjamin I. Goldstein, M.D., Ph.D.,6 Mary Kay Gill, M.S.N.,5 Neal D. Ryan, M.D.,5 Michael Strober, Ph.D.,7 Boris Birmaher, M.D.,5 and…

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Computational Psychiatry in Borderline Personality Disorder

Computational Psychiatry in Borderline Personality Disorder

Curr Behav Neurosci Rep. Author manuscript; available in PMC 2018 Mar 1. Published in final edited form as: Curr Behav Neurosci Rep. 2017 Mar; 4(1): 31–40. Published online 2017 Feb 4. doi: 10.1007/s40473-017-0104-y PMCID: PMC5499688 NIHMSID: NIHMS871001 PMID: 28690972 Sarah K Fineberg, MD, PhD,*,1 Dylan Stahl,1,2 and Philip Corlett, PhD1 Author information Copyright and License information Disclaimer The publisher’s final edited version of this article is available at Curr Behav Neurosci Rep See other articles in PMC that cite the published…

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The specificity of emotion dysregulation in adolescents with borderline personality disorder: comparison with psychiatric and healthy controls

The specificity of emotion dysregulation in adolescents with borderline personality disorder: comparison with psychiatric and healthy controls

Borderline Personal Disord Emot Dysregul. 2017; 4: 1. Published online 2017 Jan 10. doi: 10.1186/s40479-017-0052-x PMCID: PMC5223469 PMID: 28078089 Marina Ibraheim, Allison Kalpakci, and Carla Sharp Author information Article notes Copyright and License information Disclaimer This article has been cited by other articles in PMC. Associated Data Data Availability Statement Abstract Background Research has supported the notion that emotion dysregulation is a core feature of BPD. However, given that this feature is typical of healthy adolescents as well as adolescents with…

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Borderline Personality Disorder (BPD): In the Midst of Vulnerability, Chaos, and Awe

Borderline Personality Disorder (BPD): In the Midst of Vulnerability, Chaos, and Awe

Brain Sci. 2018 Nov; 8(11): 201. Published online 2018 Nov 18. doi: 10.3390/brainsci8110201 PMCID: PMC6266914 PMID: 30453675 Filiz Kulacaoglu1 and Samet Kose2,3,4,* Author information Article notes Copyright and License information Disclaimer Abstract Borderline personality disorder (BPD) is a chronic psychiatric disorder characterized by pervasive affective instability, self-image disturbances, impulsivity, marked suicidality, and unstable interpersonal relationships as the core dimensions of psychopathology underlying the disorder. Across a wide range of situations, BPD causes significant impairments. Patients with BPD suffer considerable morbidity and…

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