Browsed by
Tag: prefrontal cortex

Post-Traumatic Stress Disorder: The Relationship Between the Fear Response and Chronic Stress

Post-Traumatic Stress Disorder: The Relationship Between the Fear Response and Chronic Stress

Lisa Y Maeng, Mohammed R Milad First Published June 27, 2017 Review Article  https://doi.org/10.1177/2470547017713297   Abstract Post-traumatic stress disorder (PTSD) is a disabling psychiatric condition that can develop following a physical, psychological, or sexual trauma. Despite the growing body of literature examining the psychological and biological factors involved in PTSD psychopathology, specific biomarkers that may improve diagnosis and treatment of PTSD have yet to be identified and validated. This challenge may be attributed to the diverse array of symptoms that…

Read More Read More

Trustworthiness appraisal deficits in borderline personality disorder are associated with prefrontal cortex, not amygdala, impairment

Trustworthiness appraisal deficits in borderline personality disorder are associated with prefrontal cortex, not amygdala, impairment

Eric A.Fertuckabc JackGrinbandbcd J. JohnMannbc JoyHirschde KevinOchsnerf PaulPilkonisg JeffErbeac BarbaraStanleybc https://doi.org/10.1016/j.nicl.2018.101616Get rights and content Under a Creative Commons license open access Highlights •BPD is associated with sensitivity to signals of interpersonal betrayal and misplaced trust in others. •BPD subjects judged faces to be less trustworthy than controls. •Amygdala activity did not correlate with trustworthiness, but was modulated robustly by fearfulness of the stimulus. •Prefrontal cortex, not amygdala, was modulated by trustworthiness. •BPD was associated with reduced prefrontal activity, and the…

Read More Read More

Antisocial Personality Disorders

Antisocial Personality Disorders

  Glenn, A.L. & Raine, A. (2011). Antisocial Personality Disorders. In J. Decety & J. Cacioppo (Eds.) The Oxford Handbook of Social Neuroscience (pp. 885-894). New York: Oxford University Press.     Antisocial Personality Disorders Andrea L. Glenn1  & Adrian Raine2 1Department of Psychology, University of Pennsylvania, 3720 Walnut Street, Philadelphia, PA 19104, United States 2Departments of Criminology, Psychiatry, and Psychology, University of Pennsylvania, 3720 Walnut Street, Philadelphia, PA 19104, United States   Abstract Neuroscience research is beginning to uncover…

Read More Read More