Trustworthiness appraisal deficits in borderline personality disorder are associated with prefrontal cortex, not amygdala, impairment
Eric A.Fertuckabc JackGrinbandbcd J. JohnMannbc JoyHirschde KevinOchsnerf PaulPilkonisg JeffErbeac BarbaraStanleybc https://doi.org/10.1016/j.nicl.2018.101616Get rights and content Under a Creative Commons license open access Highlights •BPD is associated with sensitivity to signals of interpersonal betrayal and misplaced trust in others. •BPD subjects judged faces to be less trustworthy than controls. •Amygdala activity did not correlate with trustworthiness, but was modulated robustly by fearfulness of the stimulus. •Prefrontal cortex, not amygdala, was modulated by trustworthiness. •BPD was associated with reduced prefrontal activity, and the…
