Browsed by
Month: May 2025

Association between childhood maltreatment, psychopathology and DNA methylation of genes involved in stress regulation: Evidence from a study in Borderline Personality Disorder

Association between childhood maltreatment, psychopathology and DNA methylation of genes involved in stress regulation: Evidence from a study in Borderline Personality Disorder

Comments 0 Comment

Open Access Peer-reviewed Research Article Vera Flasbeck, Martin Brüne Published: March 11, 2021 https://doi.org/10.1371/journal.pone.0248514 Abstract Previous research suggests that childhood maltreatment is associated with epigenetic modification of genes involved in hypothalamic-pituitary-adrenal (HPA) functioning, which could cause dysregulation of the stress response system. If pervasive, this may be associated with the development of stress-related disorder in adults, including affective disorders, anxiety disorders, post-traumatic stress disorder (PTSD) or borderline-personality disorder (BPD). The majority of studies have focused on DNA methylation of the…

Read More Read More

Predictors of Natural and Unnatural Mortality among Patients with Personality Disorder: Evidence from a Large UK Case Register

Predictors of Natural and Unnatural Mortality among Patients with Personality Disorder: Evidence from a Large UK Case Register

Comments 0 Comment

Open Access Peer-reviewed Research Article Marcella Lei-Yee Fok , Robert Stewart, Richard D. Hayes , Paul Moran Published: July 7, 2014 https://doi.org/10.1371/journal.pone.0100979 Abstract Background People with personality disorder have reduced life expectancy, yet, within this population, little is known about the clinical predictors of natural and unnatural deaths. We set out to investigate this, using a large cohort of secondary mental health patients with personality disorder. Methods We identified patients with an ICD-10 diagnosis of personality disorder, aged ≥15 years…

Read More Read More

Monitoring the emotional facial reactions of individuals with antisocial personality disorder during the retrieval of self-defining memories

Monitoring the emotional facial reactions of individuals with antisocial personality disorder during the retrieval of self-defining memories

Comments 0 Comment

Open Access Peer-reviewed Research Article Audrey Lavallee, Thierry. H. Pham, Marie-Charlotte Gandolphe, Xavier Saloppé, Laurent Ott, Jean-Louis Nandrino Published: June 8, 2022 https://doi.org/10.1371/journal.pone.0268818 Abstract While a deficit in the recognition of facial expression has been demonstrated in persons with antisocial personality disorder (ASPD), few studies have investigated how individuals with ASPD produce their own emotional facial expressions. This study examines the production of facial emotional expressions of male inpatients with ASPD in a forensic hospital compared with a control group…

Read More Read More

Are narcissists more attracted to people in relationships than to people not in relationships?

Are narcissists more attracted to people in relationships than to people not in relationships?

Comments 0 Comment

Open Access Peer-reviewed Research Article Amy B. Brunell , Joshua Robison , Nicholas P. Deems , Bradley M. Okdie Published: March 27, 2018 https://doi.org/10.1371/journal.pone.0194106 Abstract Does grandiose narcissism predict greater attraction for others in relationships? We examined this question by replicating previous work implicating grandiose narcissists as mate poachers (Studies 1 and 2). We then used an experimental paradigm (Studies 3 and 4) to assess the extent to which grandiose narcissists indicate a greater interest in someone who is already…

Read More Read More