In Search of the Trauma Memory: A Meta-Analysis of Functional Neuroimaging Studies of Symptom Provocation in Posttraumatic Stress Disorder (PTSD)
Open Access Peer-reviewed Research Article Gudrun Sartory , Jan Cwik, Helge Knuppertz, Benjamin Schürholt, Morena Lebens, Rüdiger J. Seitz, Ralf Schulze Published: March 25, 2013 https://doi.org/10.1371/journal.pone.0058150 Abstract Notwithstanding some discrepancy between results from neuroimaging studies of symptom provocation in posttraumatic stress disorder (PTSD), there is broad agreement as to the neural circuit underlying this disorder. It is thought to be characterized by an exaggerated amygdalar and decreased medial prefrontal activation to which the elevated anxiety state and concomitant inadequate emotional…