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Author: Andre Venter

Association between childhood maltreatment, psychopathology and DNA methylation of genes involved in stress regulation: Evidence from a study in Borderline Personality Disorder

Association between childhood maltreatment, psychopathology and DNA methylation of genes involved in stress regulation: Evidence from a study in Borderline Personality Disorder

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Open Access Peer-reviewed Research Article Vera Flasbeck, Martin Brüne Published: March 11, 2021 https://doi.org/10.1371/journal.pone.0248514 Abstract Previous research suggests that childhood maltreatment is associated with epigenetic modification of genes involved in hypothalamic-pituitary-adrenal (HPA) functioning, which could cause dysregulation of the stress response system. If pervasive, this may be associated with the development of stress-related disorder in adults, including affective disorders, anxiety disorders, post-traumatic stress disorder (PTSD) or borderline-personality disorder (BPD). The majority of studies have focused on DNA methylation of the…

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Predictors of Natural and Unnatural Mortality among Patients with Personality Disorder: Evidence from a Large UK Case Register

Predictors of Natural and Unnatural Mortality among Patients with Personality Disorder: Evidence from a Large UK Case Register

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Open Access Peer-reviewed Research Article Marcella Lei-Yee Fok , Robert Stewart, Richard D. Hayes , Paul Moran Published: July 7, 2014 https://doi.org/10.1371/journal.pone.0100979 Abstract Background People with personality disorder have reduced life expectancy, yet, within this population, little is known about the clinical predictors of natural and unnatural deaths. We set out to investigate this, using a large cohort of secondary mental health patients with personality disorder. Methods We identified patients with an ICD-10 diagnosis of personality disorder, aged ≥15 years…

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Monitoring the emotional facial reactions of individuals with antisocial personality disorder during the retrieval of self-defining memories

Monitoring the emotional facial reactions of individuals with antisocial personality disorder during the retrieval of self-defining memories

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Open Access Peer-reviewed Research Article Audrey Lavallee, Thierry. H. Pham, Marie-Charlotte Gandolphe, Xavier Saloppé, Laurent Ott, Jean-Louis Nandrino Published: June 8, 2022 https://doi.org/10.1371/journal.pone.0268818 Abstract While a deficit in the recognition of facial expression has been demonstrated in persons with antisocial personality disorder (ASPD), few studies have investigated how individuals with ASPD produce their own emotional facial expressions. This study examines the production of facial emotional expressions of male inpatients with ASPD in a forensic hospital compared with a control group…

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Are narcissists more attracted to people in relationships than to people not in relationships?

Are narcissists more attracted to people in relationships than to people not in relationships?

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Open Access Peer-reviewed Research Article Amy B. Brunell , Joshua Robison , Nicholas P. Deems , Bradley M. Okdie Published: March 27, 2018 https://doi.org/10.1371/journal.pone.0194106 Abstract Does grandiose narcissism predict greater attraction for others in relationships? We examined this question by replicating previous work implicating grandiose narcissists as mate poachers (Studies 1 and 2). We then used an experimental paradigm (Studies 3 and 4) to assess the extent to which grandiose narcissists indicate a greater interest in someone who is already…

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A Behavioral Genetic Study of Intrapersonal and Interpersonal Dimensions of Narcissism

A Behavioral Genetic Study of Intrapersonal and Interpersonal Dimensions of Narcissism

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Open Access Peer-reviewed Research Article Yu L. L. Luo, Huajian Cai , Hairong Song Published: April 2, 2014 https://doi.org/10.1371/journal.pone.0093403   Abstract Narcissism, characterized by grandiose self-image and entitled feelings to others, has been increasingly prevalent in the past decades. This study examined genetic and environmental bases of two dimensions of narcissism: intrapersonal grandiosity and interpersonal entitlement. A total of 304 pairs of twins from Beijing, China completed the Narcissistic Grandiosity Scale and the Psychological Entitlement Scale. Both grandiosity (23%) and…

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Suicide and sudden violent death among young people: Two sides of the same coin?

Suicide and sudden violent death among young people: Two sides of the same coin?

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Open Access Peer-reviewed Research Article Annelie Werbart Törnblom , Andrzej Werbart , Kimmo Sorjonen , Bo Runeson Published: December 4, 2024 https://doi.org/10.1371/journal.pone.0313673   Abstract The aim of the present study was to compare risk factors for death by suicide and sudden violent death (SVD) among young people aged 10–25 years. Two target samples, 63 consecutive cases of youth suicide and 62 cases of SVD, were compared on potential risk factors differentiating the two groups from 104 controls. Data on psychiatric…

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Brain Structural Alterations in Obsessive-Compulsive Disorder Patients with Autogenous and Reactive Obsessions

Brain Structural Alterations in Obsessive-Compulsive Disorder Patients with Autogenous and Reactive Obsessions

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Open Access Peer-reviewed Research Article Marta Subirà, Pino Alonso, Cinto Segalàs, Eva Real, Clara López-Solà, Jesús Pujol, Ignacio Martínez-Zalacaín, Ben J. Harrison, José M. Menchón, Narcís Cardoner, Carles Soriano-Mas Published: September 30, 2013 https://doi.org/10.1371/journal.pone.0075273 Abstract Obsessive-compulsive disorder (OCD) is a clinically heterogeneous condition. Although structural brain alterations have been consistently reported in OCD, their interaction with particular clinical subtypes deserves further examination. Among other approaches, a two-group classification in patients with autogenous and reactive obsessions has been proposed. The purpose…

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Mental disorders and criminal legal involvement: Evidence from a national diagnostic epidemiological survey

Mental disorders and criminal legal involvement: Evidence from a national diagnostic epidemiological survey

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Open Access Peer-reviewed Research Article Jeffrey W. Swanson , Madeline Stenger, Michele M. Easter, Natalie Bareis, Lydia Chwastiak, Lisa B. Dixon, Mark J. Edlund, Scott Graupensperger, Heidi Guyer, Maria  Monroe-DeVita, Mark Olfson, T. Scott Stroup, Katherine S. Winans, Marvin S. Swartz Published: April 9, 2025 https://doi.org/10.1371/journal.pmen.0000257 Abstract Large numbers of adults with mental disorders in the United States are incarcerated or otherwise involved with the criminal legal system. Evidence is lacking on prevalence of specific psychiatric diagnoses in this population. This…

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Longitudinal measurement invariance of the Child Problematic Trait Inventory in older Chinese children

Longitudinal measurement invariance of the Child Problematic Trait Inventory in older Chinese children

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Open Access Peer-reviewed Research Article Jie Luo, Xuetong Wang , Meng-Cheng Wang , Xintong Zhang, Jiaxin Deng, Chuxian Zhong, Yu Gao, Shi-san Qi Published: July 3, 2019 https://doi.org/10.1371/journal.pone.0219136 Abstract The Child Problematic Traits Inventory (CPTI) is a newly developed informant-rated instrument to measure psychopathic traits during early childhood. The aim of this study was to examine the longitudinal measurement invariance of the CPTI in a group of Chinese schoolchildren. Mothers of 585 children aged 8 to 12 years (50% girls)…

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The significance of anxiety symptoms in predicting psychosocial functioning across borderline personality traits

The significance of anxiety symptoms in predicting psychosocial functioning across borderline personality traits

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Open Access Peer-reviewed Research Article Jacqueline Howard, Howard J, de Jesús-Romeroo, Allison Peipert, Tennisha Riley, Lauren A. Rutter, Lorenzo Lorenzo-Luaces Published: January 27, 2021 https://doi.org/10.1371/journal.pone.0245099 Abstract Emotion regulation is a central task of daily life. Difficulty regulating emotions is a core feature of borderline personality disorder (BPD), one of the most common and impairing personality disorder diagnoses. While anger and symptoms of depression are instantiated in the criteria for BPD, anxiety is not, despite being among the most common psychiatric…

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