Browsed by
Category: Personality Disorder

Abnormal Anatomical Connectivity between the Amygdala and Orbitofrontal Cortex in Conduct Disorder

Abnormal Anatomical Connectivity between the Amygdala and Orbitofrontal Cortex in Conduct Disorder

Comments 0 Comment

Open Access Peer-reviewed Research Article Luca Passamonti , Graeme Fairchild, Alex Fornito, Ian M. Goodyer, Ian Nimmo-Smith, Cindy C. Hagan, Andrew J. Calder Published: November 7, 2012 https://doi.org/10.1371/journal.pone.0048789 Abstract Objective Previous research suggested that structural and functional abnormalities within the amygdala and orbitofrontal cortex contribute to the pathophysiology of Conduct Disorder (CD). Here, we investigated whether the integrity of the white-matter pathways connecting these regions is abnormal and thus may represent a putative neurobiological marker for CD. Methods Diffusion Tensor…

Read More Read More

Stable self-serving personality traits in recreational and dependent cocaine users

Stable self-serving personality traits in recreational and dependent cocaine users

Comments 0 Comment

Open Access Peer-reviewed Research Article Boris B. Quednow, Lea M. Hulka, Katrin H. Preller, Markus R. Baumgartner, Christoph Eisenegger, Matthias Vonmoos Published: March 2, 2017 https://doi.org/10.1371/journal.pone.0172853 Abstract Chronic cocaine use has been associated with impairments in social cognition, self-serving and antisocial behavior, and socially relevant personality disorders (PD). Despite the apparent relationship between Machiavellianism and stimulant use, no study has explicitly examined this personality concept in cocaine users so far. In the frame of the longitudinal Zurich Cocaine Cognition Study,…

Read More Read More

Dispositional and ideological factor correlate of conspiracy thinking and beliefs

Dispositional and ideological factor correlate of conspiracy thinking and beliefs

Comments 0 Comment

Open Access Peer-reviewed Research Article Jan Ketil Arnulf, Charlotte Robinson, Adrian Furnham Published: October 26, 2022 https://doi.org/10.1371/journal.pone.0273763 Abstract This study explored how the Big Five personality traits, as well as measures of personality disorders, are related to two different measures of conspiracy theories (CTs)The two measures correlated r = .58 and were applied to examine generalisability of findings. We also measured participants (N = 397) general knowledge levels and ideology in the form of religious and political beliefs. Results show…

Read More Read More

Translating trait to state assessment: The case of grandiose narcissism

Translating trait to state assessment: The case of grandiose narcissism

Comments 0 Comment

Open Access Peer-reviewed Research Article Fien Heyde , Bart Wille, Evy Kuijpers, Jasmine Vergauwe, Joeri Hofmans Published: May 1, 2023 https://doi.org/10.1371/journal.pone.0284649 Abstract Although interest in within-person variability in grandiose narcissism is growing, measurement tools are lacking that allow studying fluctuations in this personality characteristic in a differentiated manner (i.e., distinguishing narcissistic admiration and rivalry). This study explores whether a measurement approach using the six-item version of the Narcissistic Grandiosity Scale (NGS Rosenthal et al. (2007)) and six additional newly formulated…

Read More Read More

Pain perception in personality disorders

Pain perception in personality disorders

Comments 0 Comment

Open Access Peer-reviewed Research Article Spyridoula Bourtzoni, Phil Reed Published: May 9, 2025 https://doi.org/10.1371/journal.pone.0323004 Abstract Research has focused on pain perception of individuals with Borderline Personality Disorder, but there is a lack of research regarding pain perception for other types of Personality Disorders. The present study explored associations between the perception of experimentally-induced acute pain of individuals without acute or chronic pain with Borderline, as well as Histrionic, and Schizotypal, Personality Disorders traits. The primary question of interest was whether…

Read More Read More

A Whole-Brain Investigation of White Matter Microstructure in Adolescents with Conduct Disorder

A Whole-Brain Investigation of White Matter Microstructure in Adolescents with Conduct Disorder

Comments 0 Comment

Open Access Peer-reviewed Research Article Sagari Sarkar, Flavio Dell’Acqua, Seán Froudist Walsh, Nigel Blackwood, Stephen Scott, Michael C. Craig, Quinton Deeley, Declan G. M. Murphy Published: June 6, 2016 https://doi.org/10.1371/journal.pone.0155475 Abstract Background The biological basis of severe antisocial behaviour in adolescents is poorly understood. We recently reported that adolescents with conduct disorder (CD) have significantly increased fractional anisotropy (FA) of the uncinate fasciculus (a white matter (WM) tract that connects the amygdala to the frontal lobe) compared to their non-CD…

Read More Read More

Personality and psychopathological characteristics in functional movement disorders

Personality and psychopathological characteristics in functional movement disorders

Comments 0 Comment

Open Access Peer-reviewed Research Article Antonina Luca, Tiziana Lo Castro, Giovanni Mostile, Giulia Donzuso, Calogero Edoardo Cicero, Alessandra Nicoletti, Mario Zappia Published: May 10, 2024 https://doi.org/10.1371/journal.pone.0303379 Abstract Introduction Aim of the present study was to assess personality and psychopathological characteristics in patients with functional movement disorders (FMDs) compared to patients with other neurological disorders (OND).   Methods In this cross-sectional study, patients affected by clinically established FMDs and OND who attended the Neurologic Unit of the University-Hospital “Policlinico-San Marco” of…

Read More Read More

Psychopathic tendencies are selectively associated with reduced emotional awareness in the context of early adversity

Psychopathic tendencies are selectively associated with reduced emotional awareness in the context of early adversity

Comments 0 Comment

Open Access Peer-reviewed Research Article Ryan Smith ,Anne E. Chuning, Colin A. Tidwell, John J. B. Allen, Richard D. Lane Published: December 22, 2022 https://doi.org/10.1371/journal.pone.0277475 Abstract It is unclear at present whether psychopathic tendencies are associated with lower or higher levels of emotional awareness (EA). Given that psychopathy includes a proficiency for manipulating others, one might expect an elevated ability to identify and use information about others’ emotions. On the other hand, empathic deficits in psychopathy could arise from reduced…

Read More Read More

Evaluation of international guidance for the community treatment of ‘personality disorders’: A systematic review

Evaluation of international guidance for the community treatment of ‘personality disorders’: A systematic review

Comments 0 Comment

Open Access Peer-reviewed Research Article Nicholas Zhan Yuen Wong, Phoebe Barnett, Luke Sheridan Rains, Sonia Johnson, Jo Billings Published: March 13, 2023 https://doi.org/10.1371/journal.pone.0264239 Abstract Background Guidelines for the treatment and management of ‘personality disorders’ have been introduced to provide guidance on best practice based on evidence and views of key stakeholders. However, guidance varies and there is yet to be an overall, internationally recognised consensus on the best mental health care for people with ‘personality disorders’. Aims We aimed to…

Read More Read More

Association between childhood maltreatment, psychopathology and DNA methylation of genes involved in stress regulation: Evidence from a study in Borderline Personality Disorder

Association between childhood maltreatment, psychopathology and DNA methylation of genes involved in stress regulation: Evidence from a study in Borderline Personality Disorder

Comments 0 Comment

Open Access Peer-reviewed Research Article Vera Flasbeck, Martin Brüne Published: March 11, 2021 https://doi.org/10.1371/journal.pone.0248514 Abstract Previous research suggests that childhood maltreatment is associated with epigenetic modification of genes involved in hypothalamic-pituitary-adrenal (HPA) functioning, which could cause dysregulation of the stress response system. If pervasive, this may be associated with the development of stress-related disorder in adults, including affective disorders, anxiety disorders, post-traumatic stress disorder (PTSD) or borderline-personality disorder (BPD). The majority of studies have focused on DNA methylation of the…

Read More Read More