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Tag: Bipolar Disorder

Lithium Impacts on the Amplitude and Period of the Molecular Circadian Clockwork

Lithium Impacts on the Amplitude and Period of the Molecular Circadian Clockwork

Open Access Peer-reviewed Research Article Jian Li, Wei-Qun Lu, Stephen Beesley, Andrew S. I. Loudon , Qing-Jun Meng Published: March 12, 2012 https://doi.org/10.1371/journal.pone.0033292 Abstract Lithium salt has been widely used in treatment of Bipolar Disorder, a mental disturbance associated with circadian rhythm disruptions. Lithium mildly but consistently lengthens circadian period of behavioural rhythms in multiple organisms. To systematically address the impacts of lithium on circadian pacemaking and the underlying mechanisms, we measured locomotor activity in mice in vivo following chronic lithium…

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The lived experience of caring for someone with bipolar disorder: A qualitative study

The lived experience of caring for someone with bipolar disorder: A qualitative study

Open Access Peer-reviewed Research Article Bronte Speirs , Tanya L. Hanstock, Frances J. Kay-Lambkin Published: January 19, 2023 https://doi.org/10.1371/journal.pone.0280059 Abstract Being a close family or friend of someone with bipolar disorder (BD) can lead to experiences of increased stress, anxiety and depressive symptoms related to the burden of caring. However, the lived experience of being a carer for a person with BD has not received significant research attention. This study aimed to gain further insight into the experiences of individuals…

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