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Tag: Borderline Personality Disorder

Familial Resemblance of Borderline Personality Disorder Features: Genetic or Cultural Transmission?

Familial Resemblance of Borderline Personality Disorder Features: Genetic or Cultural Transmission?

Open Access Peer-reviewed Research Article Marijn A. Distel , Irene Rebollo-Mesa, Gonneke Willemsen, Catherine A. Derom, Timothy J. Trull, Nicholas G. Martin, Dorret I. Boomsma Published: April 24, 2009 https://doi.org/10.1371/journal.pone.0005334 Abstract Borderline personality disorder is a severe personality disorder for which genetic research has been limited to family studies and classical twin studies. These studies indicate that genetic effects explain 35 to 45% of the variance in borderline personality disorder and borderline personality features. However, effects of non-additive (dominance) genetic…

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The value of psychological treatment for borderline personality disorder: Systematic review and cost offset analysis of economic evaluations

The value of psychological treatment for borderline personality disorder: Systematic review and cost offset analysis of economic evaluations

Open Access Peer-reviewed Research Article Denise Meuldijk, Alexandra McCarthy, Marianne E. Bourke, Brin F. S. Grenyer   Published: March 1, 2017 https://doi.org/10.1371/journal.pone.0171592 Abstract Aim Borderline Personality Disorder (BPD) is a common mental health condition with high patterns of service utilisation of inpatient and community treatment. Over the past five years there has been significant growth in research with economic data, making this systematic review a timely update. Methods Empirical studies written in English or German, published up to December 2015,…

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The paradoxical decline and growth of trust as a function of borderline personality disorder trait count: Using discontinuous growth modelling to examine trust dynamics in response to violation and repair

The paradoxical decline and growth of trust as a function of borderline personality disorder trait count: Using discontinuous growth modelling to examine trust dynamics in response to violation and repair

Open Access Peer-reviewed Research Article Gamze Abramov , Sebastien Miellet, Jason Kautz, Brin F. S. Grenyer, Frank P. Deane Published: July 23, 2020 https://doi.org/10.1371/journal.pone.0236170 Abstract Borderline personality disorder (BPD) is associated with paradoxical trust cognitions and behaviours. While BPD is associated with difficulty forming trust and maintaining cooperation in trust-based exchanges, design and analytical methodology best suited to reveal the temporal ebb and flow of trust have been underutilized. We used an economic game to examine the trajectories of trust…

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Functional Connectivity of Pain-Mediated Affect Regulation in Borderline Personality Disorder

Functional Connectivity of Pain-Mediated Affect Regulation in Borderline Personality Disorder

Open Access Peer-reviewed Research Article Inga Niedtfeld , Peter Kirsch, Lars Schulze, Sabine C. Herpertz, Martin Bohus, Christian Schmahl Published: March 12, 2012 https://doi.org/10.1371/journal.pone.0033293 Abstract Affective instability and self-injurious behavior are important features of Borderline Personality Disorder. Whereas affective instability may be caused by a pattern of limbic hyperreactivity paired with dysfunctional prefrontal regulation mechanisms, painful stimulation was found to reduce affective arousal at the neural level, possibly underlying the soothing effect of pain in BPD. We used psychophysiological interactions…

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Gene Expression Profiles in Relation to Tension and Dissociation in Borderline Personality Disorder

Gene Expression Profiles in Relation to Tension and Dissociation in Borderline Personality Disorder

Open Access Peer-reviewed Research Article Christian Schmahl , Lars Arvastson, Joseph A. Tamm, Martin Bohus, Aicha Abdourahman, Irina Antonijevic Published: August 12, 2013 https://doi.org/10.1371/journal.pone.0070787 Abstract The biological underpinnings of borderline personality disorder (BPD) and its psychopathology including states of aversive tension and dissociation is poorly understood. Our goal was to examine transcriptional changes associated with states of tension or dissociation within individual patients in a pilot study. Dissociation is not only a critical symptom of BPD but has also been…

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Pathological grooming: Evidence for a single factor behind trichotillomania, skin picking and nail biting

Pathological grooming: Evidence for a single factor behind trichotillomania, skin picking and nail biting

Open Access Peer-reviewed Research Article Aniko Maraz , Borbála Hende, Róbert Urbán, Zsolt Demetrovics Published: September 13, 2017 https://doi.org/10.1371/journal.pone.0183806 Abstract Although trichotillomania (TTM), skin picking (SP), and nail biting (NB) have been receiving growing scientific attention, the question as to whether these disorders can be regarded as separate entities or they are different manifestations of the same underlying tendency is unclear. Data were collected online in a community survey, yielding a sample of 2705 participants (66% women, mean age: 29.1,…

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A Systematic Review of Economic Evaluations of Treatments for Borderline Personality Disorder

A Systematic Review of Economic Evaluations of Treatments for Borderline Personality Disorder

Open Access Peer-reviewed Research Article Christian Brettschneider , Steffi Riedel-Heller, Hans-Helmut König Published: September 29, 2014 https://doi.org/10.1371/journal.pone.0107748 Abstract Purpose The borderline personality disorder is a common mental disorder. It is frequently associated with various mental co-morbidities and a fundamental loss of functioning. The borderline personality disorder causes high costs to society. The aim of this study was to perform a systematic literature review of existing economic evaluations of treatments for borderline personality disorder. Materials and Methods We performed a systematic…

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Good Liars Are Neither ‘Dark’ Nor Self-Deceptive

Good Liars Are Neither ‘Dark’ Nor Self-Deceptive

Open Access Peer-reviewed Research Article Gordon R. T. Wright, Christopher J. Berry, Caroline Catmur, Geoffrey Bird Published: June 17, 2015 https://doi.org/10.1371/journal.pone.0127315 Abstract Deception is a central component of the personality ‘Dark Triad’ (Machiavellianism, Psychopathy and Narcissism). However, whether individuals exhibiting high scores on Dark Triad measures have a heightened deceptive ability has received little experimental attention. The present study tested whether the ability to lie effectively, and to detect lies told by others, was related to Dark Triad, Lie Acceptability,…

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Preserved Error-Monitoring in Borderline Personality Disorder Patients with and without Non-Suicidal Self-Injury Behaviors

Preserved Error-Monitoring in Borderline Personality Disorder Patients with and without Non-Suicidal Self-Injury Behaviors

Open Access Peer-reviewed Research Article Daniel Vega, Adrià Vilà-Balló, Àngel Soto, Julià Amengual, Joan Ribas, Rafael Torrubia, Antoni Rodríguez-Fornells, Josep Marco-Pallarés Published: December 4, 2015 https://doi.org/10.1371/journal.pone.0143994 Abstract Background The presence of non-suicidal self-injury acts in Borderline Personality Disorder (BPD) is very prevalent. These behaviors are a public health concern and have become a poorly understood phenomenon in the community. It has been proposed that the commission of non-suicidal self-injury might be related to a failure in the brain network regulating…

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Psychological therapies for adolescents with borderline personality disorder (BPD) or BPD features—A systematic review of randomized clinical trials with meta-analysis and Trial Sequential Analysis

Psychological therapies for adolescents with borderline personality disorder (BPD) or BPD features—A systematic review of randomized clinical trials with meta-analysis and Trial Sequential Analysis

Open Access Peer-reviewed Research Article Mie Sedoc Jørgensen , Ole Jakob Storebø, Jutta M. Stoffers-Winterling, Erlend Faltinsen, Adnan Todorovac, Erik Simonsen Published: January 14, 2021 https://doi.org/10.1371/journal.pone.0245331 Abstract Objectives To review the effectiveness of psychological therapies for adolescents with borderline personality disorder (BPD) or BPD features. Methods We included randomized clinical trials on psychological therapies for adolescents with BPD and BPD features. Data were extracted and assessed for quality according to Cochrane guidelines, and summarized as mean difference (MD) with 95%…

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