Psychology

Open Access Peer-reviewed Research Article Inga Niedtfeld , Peter Kirsch, Lars Schulze, Sabine C. Herpertz, Martin Bohus, Christian Schmahl Published: March 12, 2012 https://doi.org/10.1371/journal.pone.0033293 Abstract Affective instability and self-injurious behavior are important features of Borderline Personality Disorder. Whereas affective instability may be caused by a pattern of limbic hyperreactivity paired with dysfunctional prefrontal regulation mechanisms, painful stimulation was found to reduce affective arousal at the neural level, possibly underlying the soothing effect of pain in BPD. We used psychophysiological interactions…

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Open Access Peer-reviewed Research Article Christian Schmahl , Lars Arvastson, Joseph A. Tamm, Martin Bohus, Aicha Abdourahman, Irina Antonijevic Published: August 12, 2013 https://doi.org/10.1371/journal.pone.0070787 Abstract The biological underpinnings of borderline personality disorder (BPD) and its psychopathology including states of aversive tension and dissociation is poorly understood. Our goal was to examine transcriptional changes associated with states of tension or dissociation within individual patients in a pilot study. Dissociation is not only a critical symptom of BPD but has also been…

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Open Access Peer-reviewed Research Article Aniko Maraz , Borbála Hende, Róbert Urbán, Zsolt Demetrovics Published: September 13, 2017 https://doi.org/10.1371/journal.pone.0183806 Abstract Although trichotillomania (TTM), skin picking (SP), and nail biting (NB) have been receiving growing scientific attention, the question as to whether these disorders can be regarded as separate entities or they are different manifestations of the same underlying tendency is unclear. Data were collected online in a community survey, yielding a sample of 2705 participants (66% women, mean age: 29.1,…

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Open Access Peer-reviewed Research Article Christian Brettschneider , Steffi Riedel-Heller, Hans-Helmut König Published: September 29, 2014 https://doi.org/10.1371/journal.pone.0107748 Abstract Purpose The borderline personality disorder is a common mental disorder. It is frequently associated with various mental co-morbidities and a fundamental loss of functioning. The borderline personality disorder causes high costs to society. The aim of this study was to perform a systematic literature review of existing economic evaluations of treatments for borderline personality disorder. Materials and Methods We performed a systematic…

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Open Access Peer-reviewed Research Article Daniel Vega, Adrià Vilà-Balló, Àngel Soto, Julià Amengual, Joan Ribas, Rafael Torrubia, Antoni Rodríguez-Fornells, Josep Marco-Pallarés Published: December 4, 2015 https://doi.org/10.1371/journal.pone.0143994 Abstract Background The presence of non-suicidal self-injury acts in Borderline Personality Disorder (BPD) is very prevalent. These behaviors are a public health concern and have become a poorly understood phenomenon in the community. It has been proposed that the commission of non-suicidal self-injury might be related to a failure in the brain network regulating…

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Open Access Peer-reviewed Research Article Mie Sedoc Jørgensen , Ole Jakob Storebø, Jutta M. Stoffers-Winterling, Erlend Faltinsen, Adnan Todorovac, Erik Simonsen Published: January 14, 2021 https://doi.org/10.1371/journal.pone.0245331 Abstract Objectives To review the effectiveness of psychological therapies for adolescents with borderline personality disorder (BPD) or BPD features. Methods We included randomized clinical trials on psychological therapies for adolescents with BPD and BPD features. Data were extracted and assessed for quality according to Cochrane guidelines, and summarized as mean difference (MD) with 95%…

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Open Access Peer-reviewed Research Article Jeanet Grietje Nieuwenhuis , Peter Lepping, Cornelis Lambert Mulder, Henk Liewellyn Inge Nijman †, Eric Onno Noorthoorn Published: October 3, 2022 https://doi.org/10.1371/journal.pone.0272502 Abstract Purpose Little is known about the associations between mild intellectual disability (MID), borderline intellectual functioning (BIF) and aggressive behaviour in general mental health care. The study aims to establish the association between aggressive behaviour and MID/BIF, analysing patient characteristics and diagnoses. Method 1174 out of 1565 consecutive in-and outpatients were screened for…

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Open Access Peer-reviewed Research Article Charlotte C. van Schie , Laura Whiting , Brin F. S. Grenyer Published: March 28, 2024 https://doi.org/10.1371/journal.pone.0301196 Abstract Introduction A disturbed, negative sense of self is associated with various interpersonal difficulties and is characteristic of disorders such as borderline personality disorder (BPD). Negative self-views may affect an individuals’ ability to build positive relationships, including a therapeutic relationship. However, it is not yet well understood how identity disturbances give rise to interpersonal difficulties. Using an experimental…

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