Increased Prefrontal Cortical Thickness Is Associated with Enhanced Abilities to Regulate Emotions in PTSD-Free Women with Borderline Personality Disorder
Open Access Peer-reviewed Research Article Hannah Bruehl , Sandra Preißler, Isabella Heuser, Hauke R. Heekeren, Stefan Roepke , Isabel Dziobek Published: June 5, 2013 https://doi.org/10.1371/journal.pone.0065584 Abstract Previous studies suggest that amygdala, insula and prefrontal cortex (PFC) disintegrity play a crucial role in the failure to adequately regulate emotions in Borderline Personality Disorder (BPD). However, prior results are confounded by the high rate of comorbidity with Posttraumatic Stress Disorder (PTSD), which itself has been associated with changes in frontolimbic circuitry. We…