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White Matter Microstructure Alterations: A Study of Alcoholics with and without Post-Traumatic Stress Disorder

White Matter Microstructure Alterations: A Study of Alcoholics with and without Post-Traumatic Stress Disorder

Open Access Peer-reviewed Research Article Caitlin A. Durkee, Joelle E. Sarlls, Daniel W. Hommer, Reza Momenan Published: November 18, 2013 https://doi.org/10.1371/journal.pone.0080952 Abstract Many brain imaging studies have demonstrated reductions in gray and white matter volumes in alcoholism, with fewer investigators using diffusion tensor imaging (DTI) to examine the integrity of white matter pathways. Among various medical conditions, alcoholism and post-traumatic stress disorder (PTSD) are two comorbid diseases that have similar degenerative effects on the white matter integrity. Therefore, understanding and…

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