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Category: Personality Disorder

Psychophysiology of facial emotion recognition in psychopathy dimensions and oxytocin’s role: A scoping review

Psychophysiology of facial emotion recognition in psychopathy dimensions and oxytocin’s role: A scoping review

Open Access Peer-reviewed Research Article Sara Ferreira-Nascimento , Filipa Freire, Diana Prata Published: July 30, 2025 https://doi.org/10.1371/journal.pone.0327764 Abstract Psychopathy is characterized by social impairments that hinder effective societal functioning. It comprises two main dimensions: “Interpersonal-affective” and “Lifestyle-antisocial,” each associated with distinct patterns of traits and central and peripheral neurocorrelates, particularly concerning social salience and oxytocin function. In this review, we systematically identified and synthesized evidence from studies investigating oxytocin’s role in the psychophysiological correlates of emotion recognition across psychopathy dimensions….

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The paradoxical decline and growth of trust as a function of borderline personality disorder trait count: Using discontinuous growth modelling to examine trust dynamics in response to violation and repair

The paradoxical decline and growth of trust as a function of borderline personality disorder trait count: Using discontinuous growth modelling to examine trust dynamics in response to violation and repair

Open Access Peer-reviewed Research Article Gamze Abramov , Sebastien Miellet, Jason Kautz, Brin F. S. Grenyer, Frank P. Deane Published: July 23, 2020 https://doi.org/10.1371/journal.pone.0236170 Abstract Borderline personality disorder (BPD) is associated with paradoxical trust cognitions and behaviours. While BPD is associated with difficulty forming trust and maintaining cooperation in trust-based exchanges, design and analytical methodology best suited to reveal the temporal ebb and flow of trust have been underutilized. We used an economic game to examine the trajectories of trust…

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Functional Connectivity of Pain-Mediated Affect Regulation in Borderline Personality Disorder

Functional Connectivity of Pain-Mediated Affect Regulation in Borderline Personality Disorder

Open Access Peer-reviewed Research Article Inga Niedtfeld , Peter Kirsch, Lars Schulze, Sabine C. Herpertz, Martin Bohus, Christian Schmahl Published: March 12, 2012 https://doi.org/10.1371/journal.pone.0033293 Abstract Affective instability and self-injurious behavior are important features of Borderline Personality Disorder. Whereas affective instability may be caused by a pattern of limbic hyperreactivity paired with dysfunctional prefrontal regulation mechanisms, painful stimulation was found to reduce affective arousal at the neural level, possibly underlying the soothing effect of pain in BPD. We used psychophysiological interactions…

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Gene Expression Profiles in Relation to Tension and Dissociation in Borderline Personality Disorder

Gene Expression Profiles in Relation to Tension and Dissociation in Borderline Personality Disorder

Open Access Peer-reviewed Research Article Christian Schmahl , Lars Arvastson, Joseph A. Tamm, Martin Bohus, Aicha Abdourahman, Irina Antonijevic Published: August 12, 2013 https://doi.org/10.1371/journal.pone.0070787 Abstract The biological underpinnings of borderline personality disorder (BPD) and its psychopathology including states of aversive tension and dissociation is poorly understood. Our goal was to examine transcriptional changes associated with states of tension or dissociation within individual patients in a pilot study. Dissociation is not only a critical symptom of BPD but has also been…

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Pathological grooming: Evidence for a single factor behind trichotillomania, skin picking and nail biting

Pathological grooming: Evidence for a single factor behind trichotillomania, skin picking and nail biting

Open Access Peer-reviewed Research Article Aniko Maraz , Borbála Hende, Róbert Urbán, Zsolt Demetrovics Published: September 13, 2017 https://doi.org/10.1371/journal.pone.0183806 Abstract Although trichotillomania (TTM), skin picking (SP), and nail biting (NB) have been receiving growing scientific attention, the question as to whether these disorders can be regarded as separate entities or they are different manifestations of the same underlying tendency is unclear. Data were collected online in a community survey, yielding a sample of 2705 participants (66% women, mean age: 29.1,…

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A Systematic Review of Economic Evaluations of Treatments for Borderline Personality Disorder

A Systematic Review of Economic Evaluations of Treatments for Borderline Personality Disorder

Open Access Peer-reviewed Research Article Christian Brettschneider , Steffi Riedel-Heller, Hans-Helmut König Published: September 29, 2014 https://doi.org/10.1371/journal.pone.0107748 Abstract Purpose The borderline personality disorder is a common mental disorder. It is frequently associated with various mental co-morbidities and a fundamental loss of functioning. The borderline personality disorder causes high costs to society. The aim of this study was to perform a systematic literature review of existing economic evaluations of treatments for borderline personality disorder. Materials and Methods We performed a systematic…

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Grandiose narcissism associates with higher cognitive performance under stress through more efficient attention distribution: An eye-tracking study

Grandiose narcissism associates with higher cognitive performance under stress through more efficient attention distribution: An eye-tracking study

Open Access Peer-reviewed Research Article Vasilena Stefanova, Christoph Scheepers, Paul Wilson, Kostas A. Papageorgiou Published: May 3, 2024 https://doi.org/10.1371/journal.pone.0302644 Abstract Narcissism is a part of the Dark Triad that consists also of the traits of Machiavellianism and psychopathy. Two main types of narcissism exist: grandiose and vulnerable narcissism. Being a Dark Triad trait, narcissism is typically associated with negative outcomes. However, recent research suggests that at least the grandiose type may be linked (directly or indirectly) to positive outcomes including…

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Brain Structural Correlates of Emotion Recognition in Psychopaths

Brain Structural Correlates of Emotion Recognition in Psychopaths

Open Access Peer-reviewed Research Article Vanessa Pera-Guardiola , Oren Contreras-Rodríguez , Iolanda Batalla, David Kosson, José M Menchón, Josep Pifarré,Javier Bosque, Narcís Cardoner , Carles Soriano-Mas Published: May 13, 2016 https://doi.org/10.1371/journal.pone.0149807   Abstract Individuals with psychopathy present deficits in the recognition of facial emotional expressions. However, the nature and extent of these alterations are not fully understood. Furthermore, available data on the functional neural correlates of emotional face recognition deficits in adult psychopaths have provided mixed results. In this context,…

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Good Liars Are Neither ‘Dark’ Nor Self-Deceptive

Good Liars Are Neither ‘Dark’ Nor Self-Deceptive

Open Access Peer-reviewed Research Article Gordon R. T. Wright, Christopher J. Berry, Caroline Catmur, Geoffrey Bird Published: June 17, 2015 https://doi.org/10.1371/journal.pone.0127315 Abstract Deception is a central component of the personality ‘Dark Triad’ (Machiavellianism, Psychopathy and Narcissism). However, whether individuals exhibiting high scores on Dark Triad measures have a heightened deceptive ability has received little experimental attention. The present study tested whether the ability to lie effectively, and to detect lies told by others, was related to Dark Triad, Lie Acceptability,…

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Preserved Error-Monitoring in Borderline Personality Disorder Patients with and without Non-Suicidal Self-Injury Behaviors

Preserved Error-Monitoring in Borderline Personality Disorder Patients with and without Non-Suicidal Self-Injury Behaviors

Open Access Peer-reviewed Research Article Daniel Vega, Adrià Vilà-Balló, Àngel Soto, Julià Amengual, Joan Ribas, Rafael Torrubia, Antoni Rodríguez-Fornells, Josep Marco-Pallarés Published: December 4, 2015 https://doi.org/10.1371/journal.pone.0143994 Abstract Background The presence of non-suicidal self-injury acts in Borderline Personality Disorder (BPD) is very prevalent. These behaviors are a public health concern and have become a poorly understood phenomenon in the community. It has been proposed that the commission of non-suicidal self-injury might be related to a failure in the brain network regulating…

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