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Category: Eating Disorders

Atypical Antipsychotics as Augmentation Therapy in Anorexia Nervosa

Atypical Antipsychotics as Augmentation Therapy in Anorexia Nervosa

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Open Access Peer-reviewed Research Article Enrica Marzola, Nadia Desedime, Cristina Giovannone, Federico Amianto, Secondo Fassino, Giovanni Abbate-Daga Published: April 29, 2015 https://doi.org/10.1371/journal.pone.0125569 Abstract Anorexia nervosa (AN) is a life-threatening and difficult to treat mental illness with the highest mortality rates of any psychiatric disorder. We aimed to garner preliminary data on the real-world use of olanzapine and aripiprazole as augmentation agents of Selective Serotonin Reuptake Inhibitors (SSRIs) in adult inpatients affected by AN. We retrospectively evaluated the clinical charts of…

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Narcissism as a Moderator of Satisfaction with Body Image in Young Women with Extreme Underweight and Obesity

Narcissism as a Moderator of Satisfaction with Body Image in Young Women with Extreme Underweight and Obesity

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Open Access Peer-reviewed Research Article Małgorzata Lipowska , Mariusz Lipowski Published: May 11, 2015 https://doi.org/10.1371/journal.pone.0126724 Abstract Objective Body weight and age constitute main determinants of body image in women. We analyzed the role of narcissism as a moderator of body image in young women representing various extremes of body weight. Methods The study included 325 women between 18 and 35 years, qualified into three BMI categories: obese women (BMI > 30.0, n = 72), severely underweight women who did not…

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The Neuropsychology of Starvation: Set-Shifting and Central Coherence in a Fasted Nonclinical Sample

The Neuropsychology of Starvation: Set-Shifting and Central Coherence in a Fasted Nonclinical Sample

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Open Access Peer-reviewed Research Article Sarah Pender, Sam J. Gilbert, Lucy Serpell x Published: October 22, 2014 https://doi.org/10.1371/journal.pone.0110743 Abstract Objectives Recent research suggests certain neuropsychological deficits occur in anorexia nervosa (AN). The role of starvation in these deficits remains unclear. Studies of individuals without AN can elucidate our understanding of the effect of short-term starvation on neuropsychological performance. Methods Using a within-subjects repeated measures design, 60 healthy female participants were tested once after fasting for 18 hours, and once when…

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Comparison of clinical presentation and treatment response among youth with atypical anorexia nervosa and anorexia nervosa

Comparison of clinical presentation and treatment response among youth with atypical anorexia nervosa and anorexia nervosa

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Open Access Peer-reviewed Research Article Bek Urban , Kelly Cai , David M. Freestone, Megan Hellner, Cara Bohon, Adam Arsenault, Dori M. Steinberg, Jessica H. Baker Published: March 4, 2025 https://doi.org/10.1371/journal.pone.0316572 Abstract Objective Atypical anorexia nervosa (AAN) is an eating disorder that shares all symptoms with anorexia nervosa (AN) except “significantly low weight.” Here, we aim to further understand the potential similarities and differences between AN and AAN in a clinical sample of patients receiving family-based treatment (FBT) for AN…

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Characteristics of Suicide Attempts in Anorexia and Bulimia Nervosa: A Case–Control Study

Characteristics of Suicide Attempts in Anorexia and Bulimia Nervosa: A Case–Control Study

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Open Access Peer-reviewed Research Article Sébastien Guillaume , Isabelle Jaussent, Emilie Olié, Catherine Genty, Jacques Bringer, Philippe Courtet, Ulrike Schmidt Published: August 12, 2011 https://doi.org/10.1371/journal.pone.0023578 Abstract Objective Compared to other eating disorders, anorexia nervosa (AN) has the highest rates of completed suicide whereas suicide attempt rates are similar or lower than in bulimia nervosa (BN). Attempted suicide is a key predictor of suicide, thus this mismatch is intriguing. We sought to explore whether the clinical characteristics of suicidal acts differ…

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